英文原著論文

2022年

• Kimura N, Nakamura M, Takagi R, Mieno MN, Yamaguchi A, Czerny M, Beyersdorf F, Kari FA, Rylski B. False lumen/true lumen wall pressure ratio is increased in acute non-A non-B aortic dissection. Interact Cardiovasc Thorac Surg. 2022; 35: ivac138.
• Hiroshima Y, Oyama Y, Sawasaki K, Nakamura M, Kimura N, Kawahito K, Fujie H, Sakamoto N. A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction Under High Shear Stress. Ann Biomed Eng. 2022; 50: 951-963.
• Kawahito K, Aizawa K, Kimura N, Yamaguchi A, Adachi H. Influence of residual primary entry following the tear-oriented strategy for acute type A aortic dissection. Eur J Cardiothorac Surg. 2022; 61: 1077-1084.
• Kimura N, Itagaki R, Nakamura M, Tofrizal A, Yatabe M, Yoshizaki T, Kokubo R, Hishikawa S, Kunita S, Adachi H, Misawa Y, Yashiro T, Kawahito K. Bicuspidalization of the Native Tricuspid Aortic Valve: A Porcine in Vivo Model of Bicuspid Aortopathy. Ann Vasc Dis. 2022; 15: 37-44.
• Okamura H, Kusadokoro S, Mieno M, Kimura N, Yamaguchi A. Long-term outcomes after aortic valve replacement using a 19-mm bioprosthesis. Eur J Cardiothorac Surg. 2022; 61: 625-634.
• Okamura H, Arakawa M, Kitada Y, Miyagawa A, Adachi H. Bail-out pull-through pull-back technique for accidental coverage of the left common carotid artery during thoracic endovascular aortic repair. J Endovasc Ther. 2022; 29: 289-293.
• Okamura H. Sutureless repair techniques for post-infarction left ventricular free wall rupture. Ann Cardiothorac Surg. 2022; 11: 268-272.
• Okamura H, Kitada Y, Wada Y, Adachi H. Covered frozen elephant trunk technique for prevention of distal stent graft-induced new entry. Interact Cardiovasc Thorac Surg. 2022; 35: ivac033.
• Okamura H, Kitada Y, Wada Y, Fujimori T, Adachi H. Effects of a frozen elephant trunk on postoperative renal dysfunction in acute type A aortic dissection extending into the renal artery. J Card Surg. 2022; 37: 3101-3109.
• Hiraoka A, Iida Y, Furukawa T, Ueki C, Miyake K, Mieno M, Okamura H. Predictive factors of distal stent graft-induced new entry after frozen elephant trunk procedure for aortic dissection. Eur J Cardiothorac Surg. 2022; 62: vezac325.
• Okamura H, Kitada Y, Wada Y, Adachi H. Fenestrated and covered frozen elephant trunk technique for management of chronic aortic dissection. J Card Surg. 2022;37:5487-5489.
• Shiraishi M, Yamaguchi A, Suzuki K. Nrg1/ErbB signaling-mediated regulation of fibrosis after myocardial infarction. FASEB J. 2022; 36: e22150.
• Hori D, Nomura Y, Taniguchi Y, Yuri K, Mieno M, Kimura N, Yamaguchi A. The effect of stent and decalcification on mitral annular motion after aortic valve replacement. J Card Surg. 2022; 37: 2706-2712.
• Hori D, Kusadokoro S, Mieno MN, Fujimori T, Shimizu T, Kimura N, Yamaguchi A. The effect of aortic arch replacement on pulse wave velocity after surgery. Interact Cardiovasc Thorac Surg. 2022; 34: 652-659.
• Hori D, Yamamoto T, Kusadokoro S, Fujimori T, Mieno MN, Kimura N, Yamaguchi A.　Evaluation of oversizing in association with conduction disorder after implantation of a rapid deployment valve. J Artif Organs. 2022; 25: 238-244.
• Tashima Y, Iwakoshi S, Inoue T, Nakamura N, Sano T, Kimura N, Inoue T, Adachi K, Yamaguchi A. Aortic Agatston score correlates with the progression of acute type A aortic dissection. PLoS One. 2022; 17: e0263881.
• Tashima Y, Chiba Y, Ohama S, Teruaki K, Nakamura N, Sano T, Adachi K, Kimura N, Sanui M, Yamaguchi A. Effect of nadir hematocrit during cardiopulmonary bypass on the early outcomes after surgical repair of acute type A aortic dissection.　J Card Surg. 2022; 37: 2338-2347.
• Akiyoshi K, Arakawa M, Matsumoto H, Adachi K, Nakata H. Successful Crossover Bypass Using a Lateral Femoral Circumflex Artery as an Outflow Vessel for Indirect Revascularization in Critical Limb Ischemia: A Case Report. Ann Vasc Dis. 2022; 15: 333-336.
• Kusadokoro S, Kimura N. Double arterial cannulation: a classical yet useful cannulation strategy-comment on cannulation strategy in frozen elephant trunk for type A aortic dissection: double arterial cannulation approach. Eur J Cardiothorac Surg. 2022; 62: ezac231.
• Fujimori T, Okamura H, Kitada Y, Wada Y, Adachi H. Reconstruction of the left subclavian artery in arch repair: An end-to-side anastomosis technique. J Card Surg. 2022; 37: 2194-2196.
• Fujimori T, Kimura N, Mieno M, Hori D, Kusadokoro S, Tanaka M, Yamaguchi A. An increased prothrombin time-international normalized ratio in patients with acute type A aortic dissection: contributing factors and their influence on outcomes. Surg Today. 2022; 52: 431-440.
• Kitada Y, Okamura H, Kimura N, Yamaguchi A. Association between frailty and long-term outcomes among patients undergoing thoracic aortic surgery via median sternotomy. Gen Thorac Cardiovasc Surg. 2023; 71: 232-239.
• Miyagawa A, Yuri, K, Nakano M, Shinoda D, Makino J. Cardiopulmonary Bypass Surgery in a Patient with Unexpected　Heparin-Induced Thrombocytopenia. Ann Vasc Dis. 2022; 15: 352–355.

2021年

• Kimura N. Intervention for residual dissection in its early phase-comment on a prospective follow-up study after type A aortic dissection repair: a high rate of distal aneurysmal evolution and reinterventions. Eur J Cardiothorac Surg. 2021; 61: 160-161.
• Yoshinaga K, Otsuka Y, Furukawa T, Amitani S, Kimura N, Sanui M. Correlation between activated clotting time monitoring and heparin concentration measurement in a patient with antiphospholipid syndrome during cardiac valve surgery: a case report. JA Clin Rep. 2021; 7: 24.
• Ito T, Shintani Y, Fields L, Shiraishi M, Podaru MN, Kainuma S, Yamashita K, Kobayashi K, Perretti M, Lewis-McDougall F, Suzuki K. Cell barrier function of resident peritoneal macrophages in post-operative adhesions. Nat Commun. 2021; 12: 2232.
• Shiraishi M, Kimura N, Yamaguchi A. Early cardiac contractility outcome of reoperative coronary artery bypass grafting using right gastroepiploic artery. J Card Surg. 2021; 36: 4103-4110. 　　
• Tashima Y, Toyoshima Y, Chiba K, Nakamura N, Adachi K, Inoue Y, Yamaguchi A. Physical activities and surgical outcomes in elderly patients with acute type A aortic dissection. J Card Surg. 2021; 36: 2754-2764.
• Hori D, Fujimori T, Kusadokoro S, Yamamoto T, Kimura N, Yamaguchi A. Treatment site does not affect changes in pulse wave velocity but treatment length and device selection are associated with increased pulse wave velocity after thoracic endovascular aortic repair. Front Physiol. 2021; 12: 739185.
• Arakawa M, Sumikura H, Okamura H, Miyagawa A, Homma A, Yamaguchi A. A three-dimensional biomodel of type A aortic dissection for endovascular interventions. J Artif Organs. 2021; 25: 125-131.
• Nomura Y, Nakano M, Woo Sung H, Han M, Pandey D. Inhibition of HDAC6 Activity Protects Against Endothelial Dysfunction and Atherogenesis in vivo: A Role for HDAC6 Neddylation. Front Physiol. 2021; 12: 675724.
• Nakano M, Nomura Y, Whitman G, Sussman M, Schena S, Kilic A, Choi CW, Akiyoshi K, Neufeld KJ, Lawton J, Colantuoni E, Yamaguchi A, Wen M, Smielewski P, Brady K, Bush B, Hogue CW, Brown CH. Cerebral autoregulation in the operating room and intensive care unit after cardiac surgery. Br J Anaesth. 2021, 126: 967-974.
• Akiyoshi K, Boersma GJ, Johnson MD, Velasquez FC, Dunkerly-Eyring B, O'Brien S, Yamaguchi A, Steenbergen C, Tamashiro KLK, Das S. Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver. PLoS One. 2021;16:e0256973.
• Liu X, Nakano M, Yamaguchi A, Bush B, Akiyoshi K, Lee JK, Koehler RC, Hogue CW, Brown CH 4th. The association of bispectral index values and metrics of cerebral perfusion during cardiopulmonary bypass. J Clin Anesth. 2021; 74: 110395.
• Tuday E, Nakano M, Akiyoshi K, Fu X, Shah AP, Yamaguchi A, Steenbergen C, Santhanam L, An SS, Berkowitz D, Baraban JM, Das S. Degradation of Premature-miR-181b by the Translin/Trax RNase Increases Vascular Smooth Muscle Cell Stiffness. Hypertension. 2021; 78: 831-839.
• Kitada Y, Arakawa M, Okamura H, Akiyoshi K, Hori D, Kimura N, Yamaguchi A. Impact of prosthesis-patient mismatch on late outcomes after bioprosthetic mitral valve replacement for mitral regurgitation. J Artif Organs. 2021; 25: 132-139.

2020年

• Kimura N, Momose N, Kusadokoro S, Yasuda T, Kusaura R, Kokubo R, Hori D, Okamura H, Itoh S, Yuri K, Yamaguchi A. Minimized perfusion circuit for acute type A aortic dissection surgery. Artif Organs. 2020; 44: E470-E481.
• Kimura N, Nomura Y, Aomatsu A, Matsuda A, Imamura Y, Taniguchi Y, Hori D、Morishita Y, Fujita H, Yuri K, Matsumoto K, Yamaguchi A. Effect of transcatheter aortic valve implantation on the immune response associated with surgical aortic valve replacement. Am J Cardiol. 2020; 128: 35-44.
• Okamura H, Arakawa M, Kimura N, Yuri K, Yamaguchi A. Contemporary outcomes of composite aortic root replacement in elderly patients. Interact Cardiovasc Thorac Surg. 2020; 30: 443-450.
• Okamura H, Kimura N, Mieno M, Yuri K, Yamaguchi A. Preoperative sarcopenia is associated with late mortality after off-pump coronary artery bypass grafting. Eur J Cardiothorac Surg. 2020; 58: 121-129.
• Okamura H, Arakawa M, Miyagawa A, Kitada Y, Adachi H. Arch replacement for acute type A aortic dissection using a single fenestrated frozen elephant trunk technique. Ann Cardiothorac Surg. 2020; 9: 248-250.
• Okamura H, Hori D, Kusadokoro S, Mieno M, Kimura N, Yuri K, Yamaguchi A. Long-term outcomes and echocardiographic data after aortic valve replacement with a 17-mm mechanical valve. Circ J. 2020; 84: 2312-2319.
• Hori D, Nomura Y, Nakano M, Han M, Bhatta A, Chen K, Akiyoshi K, Pandey D. Endothelial-specific overexpression of histone deacetylase 2 protects mice against endothelial dysfunction and atherosclerosis. Cell Physiol Biochem. 2020; 54: 947-958.
• Hori D, Nomura Y, Nakano M, Akiyoshi K, Kimura N, Yamaguchi A. Relationship between endothelial function and vascular stiffness on lower limit of cerebral autoregulation in patients undergoing cardiovascular surgery. Artif Organs. 2020; 45: 382-389.
• Hori D, Yuri K, Kusadokoro S, Shimizu T, Kimura N, Yamaguchi A. Effect of endoprostheses on pulse wave velocity and its long-term outcomes after thoracic endovascular aortic repair. Gen Thorac Cardiovasc Surg. 2020; 68: 1134-1141.
• Hori D, Kusadokoro S, Shimizu T, Kimura N, Yamaguchi A. Prosthetic graft dilation at the aortic arch in the era of hybrid aortic surgery. Ann Vasc Dis. 2020; 13: 163-169.
• Hori D, Kusadokoro S, Kitada Y, Kimura N, Matsumoto H, Yuri K, Yamaguchi A. Prosthesis selection for aortic valve replacement in patients on hemodialysis. Gen Thorac Cardiovasc Surg. 2020; 68: 122-128.
• Hori D, Kusadokoro S, Adachi K, Kimura N, Yuri K, Matsumoto H, Yamaguchi A. Risk factors for spinal cord injury in patients undergoing frozen elephant trunk technique for acute aortic dissection. Gen Thorac Cardiovasc Surg. 2020: 68; 328-334.
• Arakawa M, Okamura H, Miyagawa A, Kitada Y, Adachi H. Clinical outcome of acute thoracic aortic syndrome in nonagenarians. Asian Cardiovasc Thorac Ann. 2020; 28: 577-582.
• Tashima Y, He H, Cui JZ, Pedroza AJ, Nakamura K, Yokoyama N, Iosef C, Burdon G, Koyano T, Yamaguchi A, Fischbein MP. Androgens Accentuate TGF-β dependent Erk/Smad activation during thoracic aortic aneurysm formation in Marfan syndrome male mice. J Am Heart Assoc. 2020; 9: e015773.
• Hashimoto K, Matsumoto H, Nonaka T, Kimura N, Yuri K, Yamaguchi A. Successful embolectomy of the plantar artery occlusion due to thromboembolism. Ann Vasc Dis. 2020;13: 465-468.
• Nakano M, Kimura N, Nonaka T, Mieno M, Tanno K, Sasabuchi Y, Kitada Y, Hori D, Yuri K, Matsumoto H, Yamaguchi A, Hanaoka K. Etiology and impact on outcomes of polycystic kidney disease in abdominal aortic aneurysm. Surg Today. 2020; 50: 1213-1222.
• Nakano M, Nomura Y, Suffredini G, Bush B, Tian J, Yamaguchi A, Walston J, Hasan R, Mandal K, Schena S, Hogue CW, Brown CH 4th. Functional outcomes of frail patients after cardiac surgery: an observational study. Anesth Analg. 2020; 130: 1534-1544.
• Tamai K, Hori D, Yuri K, Yamaguchi A. Additional frozen elephant trunk as a bailout for a misdeployed frozen elephant trunk in the false lumen in a patient with acute aortic dissection. Eur J Cardiothorac Surg. 2020; 57: 399-401.
• Yokoyama N, Nonaka T, Kimura N, Sasabuchi Y, Hori D, Matsunaga W, Fujimori　T, Miyoshi K, Matsumoto H, Yamaguchi A. Acute kidney injury following elective open aortic repair with suprarenal clamping. Ann Vasc Dis. 2020; 13: 45-51.
• Akiyoshi K，Arakawa M，Makino J，Nakamura N，Shinshi M，Nakata H，Adachi K. Off-pump coronary artery bypass grafting via left anterior thoracotomy from the 4th costal space in a patient with total laryngectomy and a permanent tracheostoma．Gen Thoracic and Cardiovascular Surg. 2020; 68: 633-636.
• Kusadokoro S, Kimura N, Hori D, Hattori M, Matsunaga W, Itagaki R, Yuri K, Mieno M, Nakamura M, Yamaguchi A. Utility of double arterial cannulation for surgical repair of acute type A dissection. Eur J Cardiothorac Surg. 2020; 57: 1068-1075.
• Kusadokoro S, Kimura N, Miyoshi K, Hori D, Shiraishi M, Yamaguchi A. Early superior mesenteric artery revascularization for acute type A aortic dissection with cardiac tamponade and mesenteric malperfusion. J Card Surg. 2020; 35: 3581-3584.
• Kusadokoro S, Hori D, Yuri K, Yamaguchi A. Dissected thoracoabdominal aortic aneurysm repair with modified parallel endografting. J Card Surg. 2020; 35: 3220-3223.
• Kusadokoro S, Hori D, Fujii K, Yamaguchi A. Left thoracotomy approach for left ventricular pseudoaneurysm due to myocardial infarction after mitral valve replacement for papillary muscle rupture. J Card Surg. 2020; 35: 2103-2105.
• Shimizu T, Kimura N, Mieno M, Hori D, Shiraishi M, Tashima Y, Yuri K, Itagaki R, Aizawa K, Kawahito K, Yamaguchi A. Effect of obesity on outcomes of acute type A aortic dissection repair in Japan. Circ Rep. 2020; 2: 639-647.
• Miyagawa A, Okamura H, Arakawa M. Successful transcatheter removal of a catheter migrating into the coronary sinus. Asian Cardiovasc Thorac Ann. 2020; 29: 343-344.
• Miyagawa A, Okamura H, Kitada Y, Arakawa M, Adachi H. Double-patch and glue repair of a postinfarction left ventricular pseudoaneurysm. Asian Cardiovasc Thorac Ann. 2020; 29: 116-118.
• Miyagawa A, Okamura H, Kitada Y, Arakawa M, Adachi H. Total arch and descending aorta replacement via left thoracotomy for infected post-thoracic endovascular aortic repair type B aortic dissection. Gen Thorac Cardiovasc Surg. 2021; 69: 346-349.
• Kitada Y, Okamura H, Arakawa M, Miyagawa A, Adachi H. Staged treatments of multiple pseudoaneurysms after total arch replacement. J Card Surg. 2020; 35: 467-469.
• Suzuki K, Kimura N, Mieno M, Hori D, Sezai A, Yamaguchi A, Tanaka M. Factors related to white blood cell elevation in acute type A aortic dissection. PLoS One. 2020; 15: e0228954.
• Ono K, Arakawa M, Nakano T, Okamura H. Hybrid surgery for anomalous systemic arterial supply to the basal segments of the lung. Interact Cardiovasc Thorac Surg. 2020; ivaa029.
• Cho Y, Wakasa S, Usui A, Minatoya K, Arai H, Yaku H, Yamaguchi A, Komiya T, Matsumiya G, Hamano K, Saiki Y, Matsui Y. Non-heart transplant surgical approaches with mitral valve operation and surgical ventricular reconstruction for non-ischaemic dilated cardiomyopathy: a Japanese multicenter study. Gen Thorac Cardiovasc Surg. 2021; 69: 679-689.
• Hasegawa H, Taniguchi Y, Sakakura K, Yamaguchi A, Fujita H. Possible thrombus formation with huge high-echoic image in the right atrium following rapid ventricular pacing during transcatheter aortic valve implantation. Cardiovasc Interv Ther. 2021; 36: 398-399.
• Kreibich M, Desai ND, Bavaria JE, Szeto WY, Vallabhajosyula P, Itagaki R, Okamura H, Kimura N, Yamaguchi A, Beyersdorf F, Czerny M, Rylski B. Preoperative neurological deficit in acute type A aortic dissection. Interact Cardiovasc Thorac Surg. 2020; 30: 613-619.
• Kreibich M, Desai ND, Bavaria JE, Szeto WY, Vallabhajosyula P, Beyersdorf F, Czerny M, Siepe M, Rylski B, Itagaki R, Okamura H, Yamaguchi A, Kimura N.　Common carotid artery true lumen flow impairment in patients with type A aortic dissection. Eur J Cardiothorac Surg. 2020; ezaa322.
• Hogue CW, Brown CH 4th, Hori D, Ono M, Nomura Y, Balmert LC, Srdanovic N, Grafman J, Brady K; Cerebral Autoregulation Study Group. Personalized blood pressure management during cardiac surgery with cerebral autoregulation monitoring: a randomized trial. Semin Thorac Cardiovasc Surg. 2021; 33: 429-438.
• Montgomery D, Brown C, Hogue CW, Brady K, Nakano M, Nomura Y, Antunes A, Addison PS. Real-Time intraoperative determination and reporting of cerebral autoregulation state using near-infrared spectroscopy. Anesth Analg. 2020; 131: 1520-1528.
• Liu X, Akiyoshi K, Nakano M, Brady K, Bush B, Nadkarni R, Venkataraman A, Koehler RC, Lee JK, Hogue CW, Czosnyka M, Smielewski P, Brown CH. Determining thresholds for three indices of autoregulation to identify the lower limit of autoregulation during cardiac surgery. Crit Care Med. 2020; 49: 650-660.
• Iosef C, Pedroza AJ, Cui JZ, Dalal AR, Arakawa M, Tashima Y, Koyano TK, Burdon G, Churovich SMP, Orrick JO, Pariani M, Fischbein MP. Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells.Sci Rep. 2020; 10: 20392.
• Fujimura N, Imazuru T, Matsumura H, Shibata T, Furuyama T, Kaneko K, Uchiyama H, Morikage N, Uchida T, Teshima E, Yamaoka T, Masuhara H, Ueda H, Arakawa M, Norimatsu T, Obara H, Onitsuka S. Two-year results of a multicenter prospective observational study of the zenith spiral-Z limb deployed in the external iliac artery during endovascular aneurysm repair. Circ J. 2020; ;84: 1764-1770.
• Pedroza AJ, Tashima Y, Shad R, Cheng P, Wirka R, Churovich S, Nakamura K, Yokoyama N, Cui JZ, Iosef C, Hiesinger W, Quertermous T, Fischbein MP. Single-cell transcriptomic profiling of vascular smooth muscle cell phenotype modulation in Marfan syndrome aortic aneurysm. Arterioscler Thromb Vasc Biol. 2020; 40: 2195-2211.
• Pedroza AJ, Koyano T, Trojan J, Rubin A, Palmon I, Jaatinen K, Burdon G, Chang P, Tashima Y, Cui JZ, Berry G, Iosef C, Fischbein MP. Divergent effects of canonical and non-canonical TGF-β signalling on mixed contractile-synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms. J Cell Mol Med. 2020; 24: 2369-2383.
• Matsuda J, Kato S, Yano H, Nitta G, Kono T, Ikenouchi T, Murata K, Kanoh M, Inamura Y, Takamiya T, Negi K, Sato A, Yamato T, Inaba O, Morita H, Matsumura Y, Nitta J, Yonetsu T. The sequential organ failure assessment (SOFA) score predicts mortality and neurological outcome in patients with post-cardiac arrest syndrome. J Cardiol. 2020; 76: 295-302.

2019年

• Ito K, Ookawara S, Ueda Y, Hayasaka H, Kofuji M, Uchida T, Matsumoto H, Yamaguchi A, Morishita Y. Improvement of bilateral lower-limb muscle oxygenation by low-density lipoprotein apheresis in a patient with peripheral artery disease undergoing hemodialysis. Nefrologia. 2019; 39: 90-92.
• Kawahito K, Kimura N, Yamaguchi A, Aizawa K. Malperfusion in type A aortic dissection: results of emergency central aortic repair. Gen Thorac Cardiovasc Surg. 2019; 67: 594-601.
• Kimura N, Aizawa K, Kawahito K, Itagaki R, Yamaguchi A, Misawa Y, Siepe M, Czerny M, Beyersdorf F, Kari FA, Rylski B. Outcomes of early-onset acute type A aortic dissection- Influence of etiologic factors. Circ J. 2019; 83: 285-294.
• Okamura H, Miyagawa A, Kitada Y, Arakawa M. Combined thoracoabdominal aortic repair and coronary artery bypass grafting in a patient with impaired left ventricular function. J Thorac Cardiovasc Surg. 2019; 158: e35-37.
• Okamura H, Arakawa M, Miyagawa A, Adachi H. Incidence of postoperative atrial fibrillation in transdermal β-blocker patch users is lower than that in oral β-blocker usersafter cardiac and/or thoracic aortic surgery. Gen Thorac Cardiovasc Surg. 2019; 67: 1007-1013.
• Okamura H. Reply: Optimal management of left ventricular free wall rupture considering the probability of re-rupture. J Thorac Cardiovasc Surg. 2019; 158: e99-100.
• Okamura H, Kimura N, Mieno M, Matsumoto, H Yuri K, Yamaguchi A. Sutureless repair for postinfarction left ventricular free wall rupture. J Thorac Cardiovasc Surg. 2019; 158: 771-777.
• Okamura H, Kimura N, Tanno K, Mieno M, Matsumoto H, Yamaguchi A, Adachi H. How is preoperative sarcopenia assessed in patients undergoing heart valve surgery? J Thorac Cardiovasc Surg. 2019; 157: e199-200.
• Okamura H, Kimura N, Tanno K, Mieno M, Matsumoto H, Yamaguchi A, Adachi H. The impact of preoperative sarcopenia, defined based on psoas muscle area, on long-term outcomes of heart valve surgery. J Thorac Cardiovasc Surg. 2019; 157: 1071-1079.
• Okamura H, Arakawa M, Takeuchi T, Adachi H. Postinfarction right ventricular wall dissection with left-to-right shunting. Interact Cardiovasc Thorac Surg. 2019; 28: 499-501.
• Okamura H, Arakawa M, Takeuchi T, Adachi H. Total fenestrated frozen elephant trunk technique for aortic repair of acute type A aortic dissection. J Thorac Cardiovasc Surg. 2019; 157: e71-73.
• Arai Y, Kimura T, Takahashi Y, Hashimoto T, Arakawa M, Okamura H. Preoperative frailty is associated with progression of postoperative cardiac rehabilitation in patients undergoing cardiovascular surgery. Gen Thorac Cardiovasc Surg. 2019; 67: 917-924.
• Hori D, Yuri K, Kusadokoro S, Katayama H, Kimura N, Yamaguchi A. Long-term outcomes of open surgery and stent graft treatment in patients undergoing repeat thoracic aortic aneurysm repair from previous anastomosis site. Ann Vasc Dis. 2019; 12: 500-506.
• Brown CH 4th, Neufeld KJ, Tian J, Probert J, LaFlam A, Max L, Hori D, Nomura Y, Mandal K, Brady K, Hogue CW; and the Cerebral Autoregulation Study Group, Shah A, Zehr K, Cameron D, Conte J, Bienvenu OJ, Gottesman R, Yamaguchi A, Kraut M. Effect of targeting mean arterial pressure during cardiopulmonary bypass by monitoring cerebral autoregulation on postsurgical delirium among older patients: A nested randomized clinical trial. JAMA Surg. 2019; 154: 819-826.
• Hori D, Nomura Y, Yamauchi T, Furuhata H, Matsumoto H, Kimura N, Yuri K, Yamaguchi A. Perioperative factors associated with aneurysm sac size changes after endovascular aneurysm repair. Surg Today. 2019; 49: 130-136.
• Arakawa M, Yuri K, Takeuchi T, Okamura H．Thoracic endovascular aortic repair for ruptured pseudocoarctation．J Thorac Cardiovasc Surg．2019; 157: 101-103.
• Kreibich M, Rylski B, Czerny M, Beyersdorf F, Itagaki R, Okamura H, Kimura N, Yamaguchi A, Vallabhajosyula P, Szeto WY, Bavaria JE, Desai ND. Impact of carotid artery involvement in type A aortic dissection. Circulation. 2019; 139: 1977-1978.
• Nomura Y, Nakano M, Bush B, Tian J, Yamaguchi A, Walston J, Hasan R, Zehr K, Mandal K, LaFlam A, Neufeld KJ, Kamath V, Hogue CW, Brown CH 4th. Observational study examining the association of baseline frailty and postcardiac surgery delirium and cognitive change. Anesth Analg. 2019; 129: 507-514.
• Yoshizaki T, Itoh S, Yamaguchi S, Numata T, Nambu A, Kimura N, Suto H, Okumura K, Sudo K, Yamaguchi A, Nakae S. IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice. Sci Rep. 2019; 9: 17067.
• Akiyoshi K, Kimura N, Aizawa K, Hori D, Okamura H, Morita H, Adachi K, Yuri K, Kawahito K, Yamaguchi A. Surgical outcomes of acute type A aortic dissection in dialysis patients. Gen Thorac Cardiovasc Surg. 2019; 67: 501-509.
• Kusadokoro S, Hori D, Itagaki R, Adachi K, Yamaguchi A. Redo descending aortic replacement via direct anastomosis to J graft open stent graft. Ann Vasc Dis. 2019; 12: 395-397.
• Kusadokoro S, Kimura N, Hori D, Yamaguchi A. Eculizumab therapy in paroxysmal nocturnal haemoglobinuria patient undergoing aortic valve surgery. Interact Cardiovasc Thorac Surg. 2019; 28: 994-995.
• Kusadokoro S, Hori D, Itagaki R, Adachi K, Yamaguchi A．Redo descending aortic replacement via direct anastomosis to J graft open stent graft．Ann Vasc Dis. 2019; 12: 395-397.
• Kitada K, Miyagawa A, Arakawa M, Okamura H. Ischemic papillary muscle rupture without significant coronary artery lesion. Interact Cardiovasc Thorac Surg.2019; 29: 971-972.
• Uchida T, Kaku Y, Hayasaka H, Kofuji M, Momose N, Miyazawa H, Ueda Y, Ito K, Ookawara S, Morishita Y．Utility of an automatic limulus amebocyte lysate kinetic turbidimetric test for endotoxin screening of dialysate samples. Med Devices (Auckl) 2019; 12: 429-433.

2018年

• Kawahito K, Kimura N, Yamaguchi A, Aizawa K, Misawa Y, Adachi H.　Early and late surgical outcomes of acute type A aortic dissection in octogenarians.　Ann Thorac Surg. 2018; 105: 137-143.
• Suzuki K, Kimura N, Sezai A, Unosawa S, Taoka M, Osaka S, Tanaka M. Successful surgical treatment of giant coronary artery aneurysm and concomitant coronary artery fistula to the pulmonary artery. Heart Surg Forum. 2018; 21: 247-249.
• Okamura H, Arakawa M, Takeuchi T, Adachi H. The fenestrated frozen elephant trunk technique for acute type A aortic dissection. J Thorac Cardiovasc Surg. 2018; 156: 75-77.
• Arai Y, Kimura T, Takahashi Y, Hashimoto T, Arakawa M, Okamura H. Preoperative nutritional status is associated with progression of postoperative cardiac rehabilitation in patients undergoing cardiovascular surgery. Gen Thorac Cardiovasc Surg. 2018; 66: 632-640.
• Shiraishi M, Adachi K, Nagano H, Yamaguchi A, Adachi H．Successful visceral revascularization after acute type A aortic dissection: How to predict visceral ischemia．Blood, Heart and Circulation．2018；Doi：10.15761/BHC.1000121.
• Hori D，Barreto Ortiz S，Nomura Y，Yun X，Jiang H，Yong H，Chen J，Paek S, Pandey D，Sikka G，Bhatta A，Gillard A，Steppan J，Kim JH，Adachi H，Barodka VM，Romer L，An SS，Shimoda LA，Santhanam L，Berkowitz DE．Opsin 3 and 4 mediate light-induced pulmonary vasorelaxation that is potentiated by G protein-coupled receptor kinase 2 inhibition．Am J Physiol Lung Cell Mol Physiol. 2018; 314: L93-106．
• Itagaki R, Kimura N, Mieno M, Hori D, Itoh S, Akiyoshi K, Yuri K, Tanno K, Kawahito K, Yamaguchi A. Characteristics and treatment outcomes of acute type A aortic dissection with elevated D-dimer concentration. J Am Heart Assoc. 2018; 7: e009144.
• Sato T, Arakawa M, Tashima Y, Tsuboi E, Burdon G, Trojan J, Koyano T, Youn YN, Penov K, Pedroza AJ, Shabazzi M, Palmon I, Nguyen MN, Connolly AJ, Yamaguchi A, Fischbein MP．Statins reduce thoracic aortic aneurysm growth in Marfan syndrome mice via inhibition of the Ras-induced ERK （extracellular signal-regulated kinase）signaling pathway. J Am Heart Assoc．2018; 7: e008543.
• Nonaka T, Kimura N, Hori D, Sasabuchi Y, Nakano M, Yuri K, Sanui M, Matsumoto H, Yamaguchi A．Predictors of Acute Kidney Injury Following Elective Open and Endovascular Aortic Repair for Abdominal Aortic Aneurysm. Ann Vasc Dis. 2018; 11: 298-305.
• Brown CH 4th, Probert J, Healy R, Parish M, Nomura Y, Yamaguchi A, Tian J, Zehr K, Mandal K, Kamath V, Neufeld KJ, Hogue CW. Cognitive decline after delirium in patients undergoing cardiac surgery. Anesthesiology. 2018; 129: 406-416.
• Nomura Y, Faegle R, Hori D, Al-Qamari A, Nemeth AJ, Gottesman R, Yenokyan G, Brown C, Hogue CW. Cerebral small vessel, but not large vessel disease, is associated with impaired cerebral autoregulation during cardiopulmonary bypass： a retrospective cohort study. Anesth Analg. 2018; 127: 1314-1322.
• Pandey D, Nomura Y, Rossberg MC, Hori D, Bhatta A, Keceli G, Leucker T, Santhanam L, Shimoda LA, Berkowitz D, Romer L．Hypoxia triggers SENP1（sentrin-specific protease 1）modulation of KLF15 （Kruppel-Like Factor 15）and transcriptional regulation of Arg2 （arginase 2）in pulmonary endothelium. Arterioscler Thromb Vasc Biol. 2018; 38: 913-926.

2017年

• Kawahito K，Kimura N，Komiya K，Nakamura M，Misawa Y．Blood flow competition after aortic valve bypass:an evaluation using computational fluid bynamics. Interat CardioVasc Thorac Surg．2017; 24: 670-676.
• Kimura N，Futamura K，Arakawa M，Okada N，Fabian Emrich，Okamura H，Sato T，Shudo Y，Koyano TK，Yamaguchi Y，Adachi H，Matsuda A，Kawahito K，Matsumoto K，Fischbein MP. Gene expression profiling of acute type A aortic dissection combined with in vitro assessment．Eur J Cardiothorac Surg. 2017; 52: 810-817.
• Kimura N，Nakamura M，Komiya K，Satoshi N，Yamaguchi A，Tanaka O，Misawa Y，Adachi H，Kawahito K．Patient-specific assessment of hemodynamics by computational fluid dynamics in patients with bicuspid aortopathy. J Thorac Cardiovasc Surg. 2017; 153: S52-S62
• Shintani Y，Ito T，Fields L，Shiraishi M，Ichihara Y，Sato N，Podaru M，Kainuma S，Tanaka H，Suzuki K．IL-4 as a repurposed biological drug for myocardial infarction through augmentation of reparative cardiac macrophages: proof-of-concept data in mice. Sci Rep. 2017; 7: 6877.
• Hori D，Akiyoshi K，Yuri K，Nishi S，Nonaka T，Yamamoto T，Imamura Y，Matsumoto H，Kimura N，Yamaguchi A．Effect of endoskeleton stent graft design on pulse wave velocity in patients undergoing endovascular repair of the aortic arch．Gen Thorac Cardiovasc Surg．2017; 65: 506-511.
• Hori D，Okamura H，Yamamoto T，Nishi S，Yuri K，Kimura N，Yamaguchi A，Adachi H．Early and mid-term outcomes of endovascular and open surgical repair of non-dissected aortic arch aneurysm. Interact Cardiovasc Thorac Surg. 2017; 24: 944-950.
• Hori D，Dunkerly-Eyring B，Nomura Y，Biswas D，Steppan J，Henao-Mejia J，Adachi H, Santhanam L, Berkowitz DE, Steenbergen C, Flavell RA, Das S．miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling. PLoS One. 2017; 12: e0174108.
• Steppan J，Bergman Y，Viegas K，Armstrong D，Tan S，Wang H，Melucci S，Hori D，Park SY， Barreto SF，Isak A，Jandu S，Flavahan N，Butlin M，An SS， Avolio A，Berkowitz DE， Halushka MK，Santhanam L．Tissue transglutaminase modulates vascular stiffness and function through crosslinking-dependent and crosslinking-independent functions. J Am Heart Assoc. 2017;6. pii: e004161.
• Chang AJ，Nomura Y，Barodka VM，Hori D，Magruder JT，Katz NM，Berkowitz DE，Hogue CW．Validation of a real-time minute-to-minute urine output monitor and the feasibility of its clinical use for patients undergoing cardiac surgery．Anesth Analg. 2017; 125: 1883-1886.
• Hori D，Nomura Y，Ono M，Joshi B，Mandal K，Cameron D，Kocherginsky M，Hogue CW．Optimal blood pressure during cardiopulmonary bypass defined by cerebral autoregulation monitoring．J Thorac Cardiovasc Surg. 2017; 154: 1590-1598.e2.
• Hori D，Yamaguchi A，Adachi H．Coronary artery bypass surgery in end-stage renal disease patients．Ann Vasc Dis. 2017; 10: 79-87.
• Hori D，Akiyoshi K，Yuri K，Nishi S，Nonaka T，Yamamoto T，Imamura Y，Matsumoto H，Kimura N，Yamaguchi A．Effect of endoskeleton stent graft design on pulse wave velocity in patients undergoing endovascular repair of the aortic arch．Gen Thorac Cardiovasc Surg．2017; 65: 506-511.
• Tashima Y, Kimura N, Tamai K, Sato K, Yuri K, Matsumoto H, Yamaguchi A, Adachi H, Kobinata T. Pulmonary stenosis caused by ductus arteriosus aneurysm: a case report. Ann Vasc Dis. 2017;10. pii: cr.16-00136.
• Tashima Y，Tamai K, Shirasugi T, Sato K, Yamamoto T, Imamura Y, Yamaguchi A，Adachi H, Kobinata T. Successful aortic banding for type IA endoleak due to neck dilatation after endovascular abdominal aortic aneurysm repair: case report. Ann Vasc Dis. 2017; 10: 265-269.
• Itagaki R，Kimura N，Itoh S，Yamaguchi A，Adachi H．Acute type A aortic dissection associated with a sporting activity. Surgery Today. 2017; 47: 1163-1171.
• Arakawa M，Hashimoto K，Okamura H．Intraoperative transprosthetic leakage of a bovine prosthetic valve after aortic valve replacement．J Thorac Cardiovasc Surg．2017: 154; 35-36.
• Nakano M，Kimura N，Matsumoto H，Hirano T，Adachi K，Yuri K，Yamaguchi A，Adachi H．Characteristics of abdominal aortic aneurysm in Japanese patients aged 50 years or younger: Ann Vasc Dis. 2017: 10: 1-6.

2016年

• Yamaguchi A, Kimura N, Itoh S, Adachi K, Yuri K, Okamura H, Adachi H. Efficacy of multiple arterial coronary bypass grafting in patients with diabetes mellitus. Eur J Cardiothorac Surg. 2016; 50: 520-527.
• Itoh S, Kimura N, Adachi H, Yamaguchi A. Is bilateral internal mammary arterial grafting beneficial for patients aged 75 years or older?　Circ J. 2016; 80: 1756-1763.
• Itoh S, Kimura N, Adachi H, Yamaguchi A. Effect of using bilateral internal mammary artery on long-term survival- reply. Circ J. 2016; 80: 2413.
• Shiraishi M, Shintani Y, Ishida H, Saba R, Yamaguchi A, Adachi H, Yashiro K, Suzuki K. Alternatively activated macrophages determine the repair of the infarcted adult murine heart．J Clin Invest. 2016; 122: 2151–2166.
• Nakada H, Arakawa M. Caregiver perspectives on end-of-life experiences of patients with left ventricular assist devices. JAMA Intern Med. 2016; 176: 1231.
• Itagaki R, Katayama I, Itoh S, Tanaka M. Three-dimensional reconstructed imaging of computed tomography of left ventricular thrombus after acute myocardial infarction. Eur J Cardiothorac Surg. 2016; 49: 1534-1535.
• Nomura Y, Yuri K, Kimura N, Okamura H, Itoh S, Matsumoto H, Yamaguchi A, Adachi H. Endovascular repair of thoracic aortic aneurysm associated with right-sided aortic arch：report of two cases. Gen Thoracic Cardiovascular Surgery. 2016; 64: 552-557.
• Yoshizaki T, Kimura N, Hirano T, Yamaguchi A, Adachi H. Acute aortic dissection occurring ”behind the wheel”, report of 11 cases. Ann Vasc Dis. 2016; 9: 205-208.
• Rylski B, Czerny M, Beyersdorf F, Kari FA, Siepe M, Adachi H, Yamaguchi A, Itagaki R, Kimura N. Is right axillary artery cannulation safe in type A aortic dissection with involvement of the innominate artery? J Thorac Cardiovas Surg. 2016; 152: 801-807.
• Sasabuchi Y, Kimura N, Shiotsuka J, Komuro T, Mouri H, Onuma T, Asaka K, Lefor AK, Yasunaga H, Yamaguchi A, Adachi H, Sanui M. Long-term survival in patients with acute kidney injury after acute type A aortic dissection repair. Ann Thorac Surg. 2016; 102: 2003-2009.
• Gupta SK, Itagaki R, Zheng X, Batkai S, Thum S, Ahmad F, Van Aelst LN, Sharma A, Piccoli MT, Weinberger F, Fiedler J, Heuser M, Heymans S, Falk CS, F?rster R, Schrepfer S, Thum T. miR-21 promotes fibrosis in an acute cardiac allograft transplantation model. Cardiovasc Res. 2016; 110: 215-226.
• Sato K, Itagaki R, Arao K, Makita K. Lifesaving treatment of acute Stanford B aortic dissection complicated by intestinal ischemia with stent placement in the superior mesenteric artery: a case report. Ann Vasc Dis. 2016; 9: 248-251.
• Guihaire J, Itagaki R, Stubbendorff M, Hua X, Deuse T, Ullrich S, Fadel E, Dorfmüller P, Robbins RC, Reichenspurner H, Schumacher U, Schrepfer S. Orthotopic tracheal transplantation using human bronchus: an original xenotransplant model of obliterative airway disorder. Transpl Int. 2016; 29: 1337-1348.
• Ishida H, Saba R, Kokkinopoulos I, Hashimoto M, Yamaguchi O, Nowotschin S, Shiraishi M, Ruchaya P, Miller D, Harmer S, Poliandri A, Kogaki S, Sakata Y, Dunkel L, Tinker A, Hadjantonakis AK, Sawa Y, Sasaki H, Ozono K, Suzuki K, Yashiro K. GFRA2 Identifies Cardiac Progenitors and mediates cardiomyocyte differentiation in a RET-independent signaling pathway. Cell Rep. 2016; 16: 1026-1038.
• Tano N, Kaneko M, Ichihara Y, Ikebe C, Coppen SR, Shiraishi M, Shintani Y, Yashiro K, Warrens A, Suzuki K. Allogeneic mesenchymal stromal cells transplanted onto the heart surface achieve therapeutic myocardial repair despite immunologic responses in rats. J Am Heart Assoc. 2016; 18; 5.
• Hori D, Katz NM, Fine DM, Ono M, Barodka VM, Lester LC, Yenokyan G, Hogue CW. Defining oliguria during cardiopulmonary bypass and its relationship with cardiac surgery-associated acute kidney injury. Br J Anaesth. 2016; 117: 733-740.
• Natarajan N, Hori D, Flavahan S, Steppan J, Flavahan NA, Berkowitz DE, Pluznick JL. Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.　Physiol Genomics. 2016; 48: 826-834.
• Hori D, Max L, Laflam A, Brown C, Neufeld KJ, Adachi H, Sciortino C, Conte JV, Cameron DE, Hogue CW Jr, Mandal K. Blood Pressure Deviations From Optimal Mean Arterial Pressure During Cardiac Surgery Measured With a Novel Monitor of Cerebral Blood Flow and Risk for Perioperative Delirium: A Pilot Study. J Cardiothorac Vasc Anesth. 2016; 30: 606-612.
• Hori D, Hogue CW. Reply. Ann Thorac Surg. 2016; 101: 2027.
• Hori D, Hogue C, Adachi H, Max L, Price J, Sciortino C, Zehr K, Conte J, Cameron D, Mandal K. Perioperative optimal blood pressure as determined by ultrasound tagged near infrared spectroscopy and its association with postoperative acute kidney injury in cardiac surgery patients. Interact Cardiovasc Thorac Surg. 2016; 22: 445-451.
• Steppan J, Sikka G, Hori D, Nyhan D, Berkowitz DE, Gottschalk A, Barodka V. Seeking a blood pressure-independent measure of vascular properties. Hypertens Res. 2016;39: 27-38.
• Rappold T, Laflam A, Hori D, Brown C, Brandt J, Mintz CD, Sieber F, Gottschalk A, Yenokyan G, Everett A, Hogue CW. Evidence of an association between brain cellular injury and cognitive decline after non-cardiac surgery. Br J Anaesth. 2016; 116:83-89.
• Hori D, Ono M, Adachi H, Hogue CW. Effect of carotid revascularization on cerebral autoregulation in combined cardiac surgery?. Eur J Cardiothorac Surg. 2016; 49: 281-287.

和文原著論文

2022年

• 堀大治郎．僧帽弁置換術後左室後壁破裂．胸部外科．2022; 75: 775-780．
• 堀大治郎．心筋梗塞後乳頭筋断裂．日本冠疾患学会誌．2022; 4: 29-33．
• 橋本和憲, 松本春信，山本貴裕, 佐藤哲也, 伊藤 智．冠動脈バイパス術後の膝窩動脈内膜摘除術の1例．日本心臓血管外科学会誌．2022; 51: 183-186．
• 中村宜由，安達晃一，佐野太一，田島泰．三尖弁感染性心内膜炎に対する右小開胸心拍動下三尖弁形成術の1例. 胸部外科．2023; 76: 127-131.
• 和田陽之介, 岡村誉, 北田悠一郎, 藤森智成, 安達秀雄. 右冠動脈領域の冠動脈攣縮が関与した下壁梗塞による乳頭筋断裂に対して僧帽弁形成術を施行した1例．日本心臓血管外科学会誌. 2022; 51: 25-30．

2021年

• 堀大治郎, 山口敦司. 再大動脈弁置換術. 胸部外科. 2021; 74: 740-745.
• 山本貴裕, 安達晃一, 堀大治郎, 藤森智成, 白石学, 木村直行, 山口敦司. 再発性多発性軟骨炎に合併し急速拡大を認めた胸部大動脈瘤. 胸部外科. 2021; 74: 583-586.

2020年

• 藤森智成，白石学, 横山野武, 野村陽平, 堀大治郎, 木村直行, 山口敦司. 僧帽弁置術術後に血栓弁を生じた抗リン脂質抗体症候群の1例. 胸部外科. 2020; 73: 619-622.

2019年

• 中村宜由, 安達晃一, 進士弥央, 秋吉慧，中田弘子. 心筋梗塞後の左室仮性瘤切除術の10年後に発生した感染性心内膜炎による左室仮性瘤の1例. 胸部外科. 2019; 72: 923-927.

2018年

• 木村直行，野中崇央，松本春信．下肢動脈病変合併冠動脈疾患の治療戦略．外科医の立場から(CABG+bypass)．冠疾患誌．2018; 24: 119-124.
• 篠田大悟，白石学，横山野武，伊藤智．心室中隔穿孔術後の遺残短絡に対する1治験例．自治医科大学紀要第41巻．2018; 41: 75-78.
• 草処翔, 安達晃一, 進士弥央, 堀大治郎，中田弘子，山口敦司. 左開胸による胸腹部大動脈置換術と冠状動脈バイパスの同時手術. 胸部外科. 2018; 71: 588-592.
• 内田隆行, 大河原晋, 早坂秀幸, 小藤誠也, 伊藤聖学, 百瀬直樹, 森下義幸．VA開存の工夫　再循環率測定を使用したバスキュラーアクセス管理．埼玉透析医学会会誌．2018; 7: 144-148.

2017年

• 百瀬直樹，徳嶺朝子，冨澤康子，人工心肺トラブルシミュレーターの制作．医療機器学．2017; 87: 495-500.
• 百瀬直樹，医療機器シミュレーション-人工心肺のトラブルシュミレーション教育-．Clinical Engineering．2017; 27: 143-146.
• 百瀬直樹．今さら聞けない補助循環―補助循環の流量管理はどうするの？―．Perfusion Saloon 2017: 9; 46-50.
• 安藤勝信．②モニタリング（1）循環血液量モニタの活用．臨床透析．2017; 33: 1190-1204.

2016年

• 安達晃一，山口敦司，由利康一，松本春信，木村直行，岡村誉，白石学，堀大治郎，安達秀雄．永久気管瘻患者に対する低侵襲アプローチによる全弓部大動脈置換術の１例．胸部外科. 2016; 69：481-484.
• 百瀬直樹，草浦理恵，梅田千典，岡田ひとみ，小山信一郎，水上由美子，遠山信幸，亀森康子，菊地浩二，山口敦司．半自動で動作する車椅子フットレストの開発．医療機器学．2016；86：267-270．

競争的研究費

文部科学省 科学研究費

研究代表者：岡村誉

ステントグラフト末端の術後新規エントリー発症機序解明のための流体?構造力学的解析　2023-2025　基盤研究（C）

研究代表者：白石学

心筋線維症の細胞分子病態の解明と遺伝子治療法の開発　2023-2025　基盤研究（C）

研究代表者：秋吉慧

大動脈の加齢に伴う硬化性変化に対するアデノシンA2A受容体拮抗薬による挑戦　2023-2025　基盤研究（C）

研究代表者：北田悠一郎

急性A型大動脈解離術後の遠隔期大動脈拡大の新たな予測因子 2022-2024 基盤研究（C）

研究代表者：木村直行　分担研究者：坂元尚哉、中村匡徳、岡村誉

血流解析研究とex vivo実験によるnonA-nonB型大動脈解離の病態解明　2021-2023　基盤研究（C）

研究代表者：堀大治郎

ステントグラフトが血管機能と主要臓器に与える影響についての検証　2021-2024　若手研究（B）

研究代表者：荒川衛

A型大動脈解離シミュレーター回路を用いたステントグラフト治療の解剖学的要件の検討2021-2023　若手研究（B）

研究代表者：白石学

心筋梗塞後の組織修復メカニズム解明と新規細胞治療法の開発　2020-2022　基盤研究（C）

研究代表者：岡村誉、分担研究者：木村直行、荒川衛

心臓?大血管手術の術後長期予後を基にしたサルコペニアの診断基準に関する検討2019-2021　基盤研究（C）

研究代表者：堀大治郎

心臓血管外科における脳自動調整能モニタリングを指標とした循環管理の有用性について2018-2021　若手研究（B）

研究代表者：木村直行、分担研究者：中村匡徳、坂元尚哉、田中正史、伊藤智

数値流体力学計算に基づく慢性大動脈解離における大動脈拡大機序の解明　2018-2020　基盤研究（C）

研究代表者：岡村誉

サルコペニアが心臓?大血管手術の予後に及ぼす影響に関する検討　2017-2018　若手研究（B）

研究代表者：白石学

心臓M２型マクロファージによる心筋梗塞発症後の組織修復メカニズムの解明　2017-2019　基盤研究（C）

研究代表者：荒川衛

植込型補助人工心臓在宅管理アプリの開発　2017-2018　若手研究（B）

研究代表者：山口敦司、分担研究者：木村直行

低侵襲心臓手術治療成績向上に向けた術後炎症反応の病態解明　2016-2018　基盤研究（C）

研究代表者：伊藤智、分担研究者：山口敦司?木村直行

IL-1受容体アンタゴニスト欠損マウスを使用した血管炎の発病メカニズムの解析2016-2018　基盤研究（C）

研究代表者：木村直行、分担研究者：山口敦司

ミニブタ大動脈弁二尖弁化による異常血流が胸部大動脈壁に及ぼす生体反応に関する検討　2015-2017　基盤研究（C）

研究代表者：山口敦司

RNAシークエンスを用いた閉鎖型人工心肺装置の有用性の検討　2013-2015 基盤研究（C）

その他の競争的研究費

白石学：dafa888手机登录_大发dafa888-官网3年度 鈴木謙三記念医科学応用研究財団　調査研究助成金　2021年度

白石学：先進医薬研究振興財団 循環医学分野 一般研究助成　2021年度

白石学：テルモ生命科学振興財団　研究助成　2021年度

岡村誉：日本心臓血管外科学会臨床研究推進助成　2020年

白石学：外科学研究助成金　研究助成、2020年度

白石学：公益財団法人 武田科学振興財団　医学系研究成金　2019年

白石学：公益財団法人 持田記念医学薬学振興財団　研究成金、2019年

白石学：金原一郎記念医学医療振興財団　第33回研究交流助成金　2019年

堀大治郎：平成30年度自治医科大学医学部研究奨励賞　2018年

白石学：平成28年度上原記念生命科学財団　研究奨励助成　2016年

白石学：平成28年度先進医薬研究振興財団　循環医学分野研究助成金　2016年